个人简介：
王琪琳，男，教授，博士生导师。河南省优秀青年基金（2024）获得者，河南省青年骨干教师，河南省化学会理事，河南省青年科技工作者协会会员，河南大学首批青年英才入选者。2014年6月毕业于中科院成都有机化学研究所，获理学博士学位。同年加入河南大学化学化工学院从事教学科研工作，2018年4月至2019年4月在美国南佛罗里达大学史晓东教授课题组交流学习。目前主要研究兴趣为多功能合成子的设计开发及其串联反应研究，用于高效构建结构复杂桥环、螺环、并环等多环体系，为药物研发提供候选分子。已经主持完成国家自然科学基金和河南省高等学校重点科研项目各一项。近三年来，以通讯作者身份在Chem. Sci.、Org. Lett.、Chem. Commun.、J. Org. Chem.、Adv. Synth. Catal.等SCI权威期刊发表学术论文25篇。受邀担任Chem. Commun.、J. Org. Chem.、Org. Biomol. Chem.等多个学术期刊审稿人。
邮箱：wangqilin@henu.edu.cn; wangqilin2005123@163.com
课题组主页：https://www.x-mol.com/groups/wang_qilin
研究方向：
新型催化剂的设计、合成及应用，不对称催化与合成，有机合成
讲授课程：
《有机合成》、《有机化学》、《有机化学实验》、《立体有机化学》
主持科研项目：
1. 吡啶盐去芳构化开环-重组新策略：氮中心多元稠环化合物的多样性不对称合成，国家自然科学基金青年基金，22101073，30万元，2022.01-2024.12.
2. 色满并吲哚啉的不对称合成，NSFC-河南人才培养联合基金，U1504206, 2016.01-2018.12.
代表性论文：
1. Le-Le Wang, Hua-Bin Han, Li-Jie Gu, Wen-Jing Zhang,* Jun-Wei Zhao* and Qi-Lin Wang.* Skeletal remodeling of chalcone-based pyridinium salts to access isoindoline polycycles and their bridged derivatives, Chem. Sci., 2021, 12, 15389-15398.
2. Hong-Jie Miao, Le-Le Wang, Hua-Bin Han, Yong-De Zhao, Qi-Lin Wang* and Zhan-Wei Bu.* Regio- and Diastereoselective Dearomatizations of N-Alkyl Activated Azaarenes: the Maximization of the Reactive Sites. Chem. Sci., 2020, 11, 1418-1424.
3. Zhao-Hui Cui, Kuan Zhang, Li-Jie Gu, Zhan-Wei Bu,* Jun-Wei Zhao* and Qi-Lin Wang.* Diastereoselective trifunctionalization of pyridinium salts to access structurally crowded azaheteropolycycles, Chem. Commun., 2021, 57, 9402-9405.
4. Shao-Jing Jin, Le-Le Wang, Hua-Bin Han, Xiong-Li Liu, Zhan-Wei Bu and Qi-Lin Wang*. Assembly of functionalized π-extended indolizine polycycles through dearomative [3+2] cycloaddition/oxidative decarbonylation, Chem. Commun., 2021, 57, 359-362.
5. Hong-Jie Miao,# Xu-Guan Bai,# Le-Le Wang, Jun-Hui Yu, Zhan-Wei Bu and Qi-Lin Wang.* Diastereoselective construction of cage-like and bridged azahetereocycles through dearomative maximization of the reactive sites of azaarenes, Org. Chem. Front., 2021, 8, 204-211.
6. Xu-Guan Bai, Hong-Jie Miao, Yang Zhao, Qi-Lin Wang* and Zhan-Wei Bu*. Regioselective and Diastereoselective Dearomative Multifunctionalization of In-Situ-Activated Azaarenes: An Access to Bridged Azahetereocycles. Org. Lett., 2020, 22, 5068-5073.
7. Le-Le Wang, Hua-Bin Han, Zhao-Hui Cui, Jun-Wei Zhao, Zhan-Wei Bu and Qi-Lin Wang*. Chalcone-Based Pyridinium Salts and Their Diastereoselective Dearomatization to Access Bibridged Benzoazepines. Org. Lett., 2020, 22, 873-878.
8. Kuan Zhang, Hua-Bin Han, Le-Le Wang, Zi-Ying Zhang, Qi-Lin Wang,* Wen-Jing Zhang* and Zhan-Wei Bu.* An unexpected cascade reaction of 3-hydroxyoxindoles with coumarin-3-carboxylates to construct 2,3-dihydrobenzofuran spirooxindoles. Chem. Commun., 2019, 55, 13681-13684.
9. Xu-Guan Bai, Le-Le Wang, Zi-Ying Zhang, Kuan Zhang, Zhan-Wei Bu, Yu-Feng Wu,* Wen-Jing Zhang* and Qi-Lin Wang.* Unexpected Cascade Reactions of Ortho-Hydroxyenaminones and β,γ-Unsaturated α-Ketoesters to Access Hydrogenated Benzoxazolepolycycles and Pyrrole Phenol Atropisomers. Adv. Synth. Catal., 2019, 361, 4893-4901.
10. Jiao-Mei Guo, Hong-Jie Miao, Yang Zhao, Xu-Guan Bai, Yan-Shuo Zhu, Qi-Lin Wang* and Zhan-Wei Bu*. An unexpected multi-component one-pot cascade reaction to access furanobenzodihydropyran-fused polycyclic heterocycles. Chem. Commun., 2019, 55, 5207-5210.
11. Shao-Jing Jin, Jia Guo, Dong-Mei Fang, Yong-Wei Huang, Qi-Lin Wang* and Zhan-Wei Bu*. A Brønsted Acid-Catalyzed Michael Addition/Cyclization Sequence for the Diastereoselective Assembly of Chroman-Bridged Polycyclic Isoindolinones. Adv. Synth. Catal., 2019, 361, 456-461.
12. Wen-Bo Wang, Xu-Guan Bai, Shao-Jing Jin, Jiao-Mei Guo, Yang Zhao, Hong-Jie Miao, Yan-Shuo Zhu, Qi-Lin Wang* and Zhan-Wei Bu*. An unexpected FeCl3-catalyzed cascade reaction of indoles and o-hydroxychalcones for the assembly of chromane-bridged polycyclic indoles. Org. Lett., 2018, 20, 3451-3454.
13. Jiao-Mei Guo, Xu-Guan Bai, Qi-Lin Wang* and Zhan-Wei Bu*. Diastereoselective Construction of Indole-Bridged Chroman Spirooxindoles through a TfOH-Catalyzed Michael Addition-Inspired Cascade Reaction. J. Org. Chem., 2018, 83, 3679-3687.
14. Yan-Shuo Zhu, Jing Zhou, Shao-Jing Jin, Hua-Hui Dong, Jiao-Mei Guo, Xu-Guan Bai, Qi-Lin Wang* and Zhan-Wei Bu*. Metal-Free Diastereoselective Construction of Bridged Ketal Spirooxindoles via Michael Addition-Inspired Sequence, Chem. Commun., 2017, 53, 11201-11204.
15. Yan-Shuo Zhu, Bei-Bei Yuan, Jiao-Mei Guo, Shao-Jing Jin, Hua-Hui Dong, Qi-Lin Wang* and Zhan-Wei Bu*. A Copper-catalyzed Friedel-Crafts alkylation/cyclization sequence: an approach to functionalized pyrrolo[1,2-a]indole spirooxindoles and 9H-pyrrolo[1,2-a]indoles, J. Org. Chem., 2017, 82, 5669-5677.
